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Article

Molecular characterization of the constitutive expression of the plasma platelet-activating factor acetylhydrolase gene in macrophages.

The Biochemical journal - 15 Oct 2003

Wu Xiaoqing, McIntyre Thomas M, Zimmerman Guy A, Prescott Stephen M, Stafforini Diana M

Abstract excerpt

Plasma platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase that inactivates platelet-activating factor (PAF) and PAF-like lipids to generate products with little or no biological activity. The levels of circulating PAF-AH correlate with several disease syndromes. We previously reported that mediators of inflammation regulate the expression of the human PAF-AH gene at the transcriptional level....

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Identifiers

PMID: 12854969
DOI: 10.1042/BJ20030636
PMCID: PMC1223687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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