Article
Cse1p is involved in export of yeast importin alpha from the nucleus.
Molecular and cellular biology - 1 Nov 1998
Solsbacher J, Maurer P, Bischoff F R, Schlenstedt G
Abstract excerpt
Proteins bearing a nuclear localization signal (NLS) are targeted to the nucleus by the heterodimeric transporter importin. Importin alpha binds to the NLS and to importin beta, which carries it through the nuclear pore complex (NPC). Importin disassembles in the nucleus, evidently by binding of RanGTP to importin beta. The importin subunits are exported separately. We investigated the role of Cse1p, the...
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