Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alpha-1-antitrypsin deficiency.

Seminars in liver disease - 1 Jan 1998

Perlmutter D H

Abstract excerpt

Homozygous PIZZ alpha 1-antitrypsin deficiency, which has an incident of 1 in 1600 to 1 in 2000 live births, is the most common genetic cause of liver disease in children. It is also associated with chronic liver disease and hepatocellular carcinoma in adults. It is a well-known cause of pulmonary emphysema. Although emphysema is due to uninhibited proteolytic destruction of the connective tissue backbone of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Neoplasms
Share to Liver Transplantation
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to alpha 1-Antitrypsin Deficiency

Share to Carcinoma, Hepatocellular

Share to Endoplasmic Reticulum

Share to Liver Diseases

Source

Identifiers

PMID: 9773422
DOI: 10.1055/s-2007-1007158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alpha-1-antitrypsin deficiency.PMID 9773422Read ↗

Liver disease in alpha 1-antitrypsin deficiency: a review.Semantic proximity Read ↗

Alpha 1-antitrypsin deficiency.Semantic proximity Read ↗

Alpha-1-antitrypsin deficiency: biochemistry and clinical manifestations.Semantic proximity Read ↗

Molecular basis, clinical consequences and diagnosis of alpha-1 antitrypsin deficiency.Semantic proximity Read ↗

Alpha 1-antitrypsin deficiency: an overview.Semantic proximity Read ↗

Liver disease in alpha-1 antitrypsin deficiency: current understanding and future therapy.Semantic proximity Read ↗

Alpha 1-antitrypsin deficiency (PiZZ): features of liver involvement in childhood.Semantic proximity Read ↗

Advances in alpha-1-antitrypsin deficiency liver disease.Semantic proximity Read ↗

Hereditary alpha-1-antitrypsin deficiency and its clinical consequences.Semantic proximity Read ↗

Alpha-1 antitrypsin deficiency: pathogenesis, clinical presentation, diagnosis, and treatment.Semantic proximity Read ↗

Mysteries of α1-antitrypsin deficiency: emerging therapeutic strategies for a challenging diseaseSemantic proximity Read ↗

Alpha-1 antitrypsin deficiency-associated liver disease: From understudied disorder to the poster child of genetic medicine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.