Article
The classical mouse mutant postaxial hemimelia results from a mutation in the Wnt 7a gene.
Developmental biology - 15 Oct 1998
Parr B A, Avery E J, Cygan J A, McMahon A P
Abstract excerpt
The study of spontaneous mutations has aided the understanding of developmental processes. A large collection of spontaneous or "classical" mouse mutations has been accumulated over many decades. One of the mutations causes the postaxial hemimelia (px) phenotype, which consists of limb patterning...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Primers
- DNA, Complementary
- Female
- Heterozygote
- Homozygote
- In Situ Hybridization
- Infertility
- Limb Deformities, Congenital
- Male
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Mullerian Ducts
- Mutation
- Phenotype