Article
Ultraviolet B induced suppression of induction of contact sensitivity in human skin is not associated with tumour necrosis factor-alpha-308 or interleukin-10 genetic polymorphisms.
The British journal of dermatology - 1 Aug 1998
Allen M H, Skov L, Barber R, Trembath R, Simon J, Baadsgaard O, Barker J N
Abstract excerpt
Low doses of ultraviolet B (UVB) can induce localized immunosuppression in skin. This effect may be important in the induction of skin cancers and is thought to be mediated by tumour necrosis factor (TNF) alpha and interleukin (IL) 10 in conjunction with other factors. In humans a transition poly...
Topics
- Alleles
- Allergens
- Cyclopropanes
- Dermatitis, Contact
- Female
- Humans
- Immune Tolerance
- Interleukin-10
- Male
- Polymorphism, Genetic
- Skin
- Tumor Necrosis Factor-alpha
- Ultraviolet Rays