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Article

Basal cell carcinoma is associated with high TNF-alpha release but nor with TNF-alpha polymorphism at position--308.

Experimental dermatology - 1 Dec 2003

Skov Lone, Allen Michael H, Bang Bo, Francis David, Barker Jonathan N W N, Baadsgaard Ole

Abstract excerpt

The mechanisms underlying induction of UVB-induced immunosuppression are not fully understood, but tumor necrosis factor alpha (TNF-alpha) is suggested to play a central role. A single base pair polymorphism at position --308 in the promoter region of the TNF-alpha gene associated with an enhanced secretion of TNF-alpha has been identified in humans. We have therefore investigated the association of the --308...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14714556
DOI: 10.1111/j.0906-6705.2003.00085.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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