Article
Alleviation of a defect in protein folding by increasing the rate of subunit assembly.
The Journal of biological chemistry - 6 Jul 2001
Aramli L A, Teschke C M
Abstract excerpt
Understanding the nature of protein grammar is critical because amino acid substitutions in some proteins cause misfolding and aggregation of the mutant protein resulting in a disease state. Amino acid substitutions in phage P22 coat protein, known as tsf (temperature-sensitive folding) mutations...
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