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Article

Evaluation of the Contraceptive Potential of Recombinant Human ZP3 and Human ZP3 Peptides in a Primate Model: Their Safety and Efficacy

1 Sept 1998

Abstract excerpt

PROBLEM: The unique recognition events that result in the avid binding of mammalian spermatozoa to the surface of the zona pellucida (ZP) are being exploited in the development of contraceptive vaccines. In this study, the safety and efficacy of a vaccination strategy based on the induction of active immunity against purified, glycosylated, recombinant human ZP3 (rhZP3) has been evaluated in a primate model,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9764365
DOI: 10.1111/j.1600-0897.1998.tb00413.x

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