Article
Effect of MTHFR genotypes and hyperhomocysteinemia on patient and graft survival in kidney transplant recipients.
Kidney international. Supplement - 1 Feb 2001
Hagen W, Födinger M, Heinz G, Buchmayer H, Hörl W H, Sunder-Plassmann G
Abstract excerpt
BACKGROUND: The total homocysteine (tHcy) plasma level, which is partly determined by the MTHFR 677C-->T genotype, may be associated with vascular disease. We prospectively examined the influence of MTHFR genotypes (677C-->T, 1298A-->C) and tHcy plasma concentration on all cause mortality and graft outcomes of renal transplant recipients. METHODS: Baseline tHcy plasma levels of 189 patients (three groups with...
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