Article
A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus.
Human genetics - 1 Aug 1998
Kidd K K, Morar B, Castiglione C M, Zhao H, Pakstis A J, Speed W C, Bonne-Tamir B, Lu R B, Goldman D, Lee C, Nam Y S, Grandy D K, Jenkins T, Kidd J R
Abstract excerpt
A four-site haplotype system at the dopamine D2 receptor locus (DRD2) has been studied in a global sample of 28 distinct populations. The haplotype system spans about 25 kb, encompassing the coding region of the gene. The four individual markers include three TaqI restriction site polymorphisms (...
Topics
- Alleles
- Base Sequence
- Biological Evolution
- DNA, Complementary
- Gene Frequency
- Genetic Variation
- Global Health
- Haplotypes
- Humans
- Linkage Disequilibrium
- Molecular Sequence Data
- Receptors, Dopamine D2