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Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region.

Gene - 20 Apr 2021

Mestiri Souhir, Boussetta Sami, Pakstis Andrew J, Elkamel Sarra, Elgaaied Amel Ben Ammar, Kidd Kenneth K, Cherni Lotfi

Abstract excerpt

The dopamine - related genes, like dopamine D2 receptor (DRD2) gene and ankyrin repeat and kinase domain containing 1 (ANKK1) gene are implicated in neurological functions. Some polymorphisms of the DRD2/ANKK1 locus (TaqIA, TaqIB, TaqID) have been used to study genetic diversity and the evolution of human populations. The present investigation aims to assess the genetic diversity in seven North African...

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PMID: 33524518
DOI: 10.1016/j.gene.2021.145466

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