Article
Haplotype diversity and linkage disequilibrium at DRD2 locus--a study on four population groups of Andhra Pradesh, India.
Genetic testing and molecular biomarkers - 1 Feb 2009
Saraswathy Kallur Nava, Mukhopadhyay Rupak, Shukla Deepti, Kaur Harpreet, Sachdeva Mohinder Pal, Rao A P, Saksena Deepti, Kalla Aloke Kumar
Abstract excerpt
Dopamine receptor D2 (DRD2) is expressed in the central nervous system and has a high affinity for many antipsychotic drugs. Besides several epidemiological investigations on association of DRD2 locus polymorphism(s) with neuropsychiatric problems and addictive behavior, a few polymorphisms in this locus have also been used to understand genomic diversity and population migratory histories globally. The present...
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