Article
Complexity and species variation of the kidney-type glutaminase gene.
Physiological genomics - 1 Jan 2002
Porter L David, Ibrahim Hend, Taylor Lynn, Curthoys Norman P
Abstract excerpt
Increased expression of rat kidney-type glutaminase (KGA) during metabolic acidosis results from selective mRNA stabilization. This process is mediated by an 8-base AU-sequence that functions as a pH-response element (pHRE). LLC-PK1-FBPase+ cells, a pH-responsive porcine kidney cell line, express...
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