Article
A screen to identify Drosophila genes required for integrin-mediated adhesion.
Genetics - 1 Oct 1998
Walsh E P, Brown N H
Abstract excerpt
Drosophila integrins have essential adhesive roles during development, including adhesion between the two wing surfaces. Most position-specific integrin mutations cause lethality, and clones of homozygous mutant cells in the wing do not adhere to the apposing surface, causing blisters. We have used FLP-FRT induced mitotic recombination to generate clones of randomly induced mutations in the F1 generation and...
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