Article
Functional analysis of the fibrinogen-related scabrous gene from Drosophila melanogaster identifies potential effector and stimulatory protein domains.
Genetics - 1 Oct 1998
Lee E C, Yu S Y, Hu X, Mlodzik M, Baker N E
Abstract excerpt
The scabrous (sca) gene encodes a secreted dimeric glycoprotein with putative coiled-coil domains N-terminally and a C-terminal region related to the blood clot protein fibrinogen. Homozygous sca mutants have extra bristle organs and rough eyes. We describe a GAL4-based expression system for test...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Conserved Sequence
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Fibrinogen
- Fungal Proteins
- Gene Expression
- Genes, Insect
- Glycoproteins
- Humans
- Insect Proteins
- Male
- Molecular Sequence Data