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Article

Maintenance of telomere length in AML

28 Nov 2017

Abstract excerpt

Abstract The importance of telomere length to human health, aging, and cancer continues to be underappreciated. This review examines some basics of telomere biology and relates how telomere function, telomerase activity, and mutations in TERC or TERT are involved in bone marrow failure, leukemias, and other cancers. Given the challenge to obtain accurate data on telomerase activity and telomere length in specific...

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PMID: 29296896
DOI: 10.1182/bloodadvances.2017012112

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