Response to interferon therapy: influence of human leucocyte antigen alleles in patients with chronic hepatitis C.

doi:10.1046/j.1365-2893.1998.00111.x

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Article

Response to interferon therapy: influence of human leucocyte antigen alleles in patients with chronic hepatitis C.

Journal of viral hepatitis - 1 Jul 1998

Sim H, Wojcik J, Margulies M, Wade J A, Heathcote J

Abstract excerpt

The response to interferon (IFN) therapy in patients with chronic hepatitis C is characterized by normalization of the serum alanine aminotransferase (ALT) activity during treatment, but relapse within 6 months of cessation of therapy is common. Viral characteristics, such as the genotype and vir...

Topics

Alanine Transaminase
Alleles
Antiviral Agents
Female
HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Hepatitis C, Chronic
Humans
Interferon-alpha
Leukocytes
Male
Middle Aged

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