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Article

Polymorphisms in the promoter of the tumor necrosis factor-alpha gene in coal miners.

American journal of industrial medicine - 1 Oct 1998

Zhai R, Jetten M, Schins R P, Franssen H, Borm P J

Abstract excerpt

Tumor necrosis factor-alpha (TNF) is recognized as a central mediator of mineral dust-induced lung fibrosis, and genetic polymorphisms of the TNF promoter have been reported to influence levels of TNF production. To assess whether polymorphisms within the TNF promoter gene are associated with susceptibility to coal workers' pneumoconiosis (CWP), the DNA of 78 coal miners was typed for G-to-A transitions at...

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Identifiers

PMID: 9750937
DOI: 10.1002/(sici)1097-0274(199810)34:4<318::aid-ajim4>3.0.co;2-o

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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