Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ascorbic acid reduced mutagenicity at the HPRT locus in CHO cells against thermal neutron radiation.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine - 1 Nov 2004

Kinashi Yuko, Sakurai Yoshinori, Masunaga Shinichiro, Suzuki Minoru, Nagata Kenji, Ono Koji

Abstract excerpt

We investigated the biological effects of the long-lived radicals induced following neutron irradiation. It has been reported that radiation-induced long-lived radicals were scavenged by post-irradiation treatment of ascorbic acid (Koyama, 1998). We studied the effects of ascorbic acid acting as a long-lived radical scavenger on cell killing and mutagenicity in Chinese hamster ovary cells against thermal neutrons...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ascorbic Acid
Share to Cell Survival

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CHO Cells

Share to Cricetinae

Share to DNA Damage

Share to Free Radical Scavengers

Share to Free Radicals

Share to Hypoxanthine Phosphoribosyltransferase

Source

Identifiers

PMID: 15308170
DOI: 10.1016/j.apradiso.2004.05.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ascorbic acid reduced mutagenicity at the HPRT locus in CHO cells against thermal neutron radiation.PMID 15308170Read ↗

Mutagenic effects at HPRT locus induced in Chinese hamster ovary cells by thermal neutrons with or without boron compound.Semantic proximity Read ↗

A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO.Semantic proximity Read ↗

A bystander effect observed in boron neutron capture therapy: a study of the induction of mutations in the HPRT locus.Semantic proximity Read ↗

Evidence that the radioprotector effect of ascorbic acid depends on the radiation dose rate.Semantic proximity Read ↗

Effect of N-acetylcysteine on Radiation-induced Genotoxicity and Cytotoxicity in Rat Bone MarrowSemantic proximity Read ↗

Mutagenic effect of borocaptate sodium and boronophenylalanine in neutron capture therapy.Semantic proximity Read ↗

Dietary supplements of antioxidants reduce hprt mutant frequency in splenocytes of aging mice.Semantic proximity Read ↗

Protective effects of ascorbic acid against radiation-induced clastogenesis.Semantic proximity Read ↗

Melatonin modulates acute testicular damage induced by carbon ions in mice.Semantic proximity Read ↗

Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions.Semantic proximity Read ↗

Antioxidative Effects of Melatonin in Protection Against Cellular Damage Caused by Ionizing RadiationSemantic proximity Read ↗

[The biological effect of the phosphatidylinositol 3-kinase wortmannin following thermal neutron irradiation].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.