Article
[Effect of beta-carotene on 60Co-gamma-induced mutation at T-lymphocyte hypoxanthine-guanine phosphoribosyl transferase locus in rats].
Zhongguo yao li xue bao = Acta pharmacologica Sinica - 1 Nov 1997
Ni Q G, Pei Y
Abstract excerpt
AIM: To study the effect of beta-carotene (beta-Car) on radiation-induced mutation. METHODS: Mutant frequency at T-lymphocyte hypoxanthine-guanine phosphoribosyl transferase (HGPRT) locus in rats was measured using a T-lymphocyte cloning technique and malondialdehyde (MDA) was measured using a thiobarbituric acid (TBA). RESULTS: Mutant frequency at the HGPRT locus was elevated by 60Co-gamma 3.75 Gy, and was...
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