The essential Escherichia coli msgB gene, a multicopy suppressor of a temperature-sensitive allele of the heat shock gene grpE, is identical to dapE.

doi:10.1128/jb.174.16.5258-5264.1992

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Article

The essential Escherichia coli msgB gene, a multicopy suppressor of a temperature-sensitive allele of the heat shock gene grpE, is identical to dapE.

Journal of bacteriology - 1 Aug 1992

Wu B, Georgopoulos C, Ang D

Abstract excerpt

The grpE gene product is one of three Escherichia coli heat shock proteins (DnaK, DnaJ, and GrpE) that are essential for both bacteriophage lambda DNA replication and bacterial growth at all temperatures. In an effort to determine the role of GrpE and to identify other factors that it may interact with, we isolated multicopy suppressors of the grpE280 point mutation, as judged by their ability to reverse the...

Topics

Alleles
Amidohydrolases
Amino Acid Sequence
Base Sequence
Chromosome Mapping
Chromosomes, Bacterial
Cloning, Molecular
DNA, Bacterial
Escherichia coli
Genes, Bacterial
Genes, Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heat-Shock Proteins

Molecular Sequence Data

Open Reading Frames

Plasmids

Restriction Mapping

Temperature

Source

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Identifiers

PMID: 1644751
DOI: 10.1128/jb.174.16.5258-5264.1992
PMCID: PMC206360

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1644751-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The essential Escherichia coli msgB gene, a multicopy suppressor of a temperature-sensitive allele of the heat shock gene grpE, is identical to dapE.PMID 1644751Read ↗

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