B cell tolerance to a minor, but not to a major, antigenic surface of the self antigen, cytochrome c.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

B cell tolerance to a minor, but not to a major, antigenic surface of the self antigen, cytochrome c.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 1998

Jemmerson R, Minnerath J M, Hedrick S M, Oehen S

Abstract excerpt

To study B cell tolerance to the mitochondrial protein cytochrome c (CYT), the B cell response to pigeon CYT (PCC) was examined in mice transgenic for PCC. PCC was coupled to OVA to provide T cell help, since PCC-specific T cells in PCC-transgenic mice are deleted in the thymus. The frequency of...

Topics

Animals
Antibodies, Monoclonal
B-Lymphocytes
Binding Sites, Antibody
Columbidae
Cytochrome c Group
Epitopes, B-Lymphocyte
Genetic Variation
Immune Sera
Lymphocyte Count
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Transgenic
Models, Molecular
Mutagenesis, Site-Directed
Self Tolerance

Source

Open in PubMed

Identifiers

PMID: 9743344

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9743344-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics