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Article

Targeting of IgMkappa antibodies to oligodendrocytes promotes CNS remyelination.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 1998

Asakura K, Miller D J, Pease L R, Rodriguez M

Abstract excerpt

We previously identified the remyelinating activity of a natural IgMkappa oligodendrocyte-reactive autoantibody (SCH94.03), using a virus-induced murine model of multiple sclerosis. We now describe a second mouse IgMkappa monoclonal antibody (mAb) (SCH79.08) raised against normal mouse spinal cord homogenate, which reacts with myelin basic protein and also promotes remyelination. Because these two mAbs recognize...

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Identifiers

PMID: 9742140
PMCID: PMC6793011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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