Article
Anti-MOG antibody: The history, clinical phenotype, and pathogenicity of a serum biomarker for demyelination.
Autoimmunity reviews - 1 Apr 2016
Ramanathan Sudarshini, Dale Russell C, Brilot Fabienne
Abstract excerpt
Myelin oligodendrocyte glycoprotein (MOG) is a protein exclusively expressed on the surface of oligodendrocytes and myelin in the central nervous system. MOG has been identified as a putative candidate autoantigen and autoantibody target in demyelination for almost three decades, with extensive literature validating its role in murine models of experimental autoimmune encephalomyelitis. Seminal studies using...
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