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Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD): Pathophysiology, Clinical Patterns, and Therapeutic Challenges of Intractable and Severe Forms

2025-08-05

Abstract excerpt

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is characterized by the predominance of optic neuritis, myelitis, acute disseminated encephalomyelitis, and cortical encephalitis, which can be diagnosed by the presence of pathogenic immunoglobulin G (IgG) antibodies targeting the extracellular domain of MOG in the serum and cerebrospinal fluid (CSF). Initially considered a variant of m...

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Literature Corpus work: 47f18d4b-b0cf-5999-9e9e-58a262e88bf9
DOI: 10.20944/preprints202508.0273.v1

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