Article
Evaluation of Lama5 as a candidate for the mouse ragged (Ra) mutation.
Biochemical and biophysical research communications - 8 Sept 1998
Durkin M E, Albrechtsen R, Chambers D M, Abbott C M, Wewer U M
Abstract excerpt
The laminin alpha5 chain is a component of the basement membranes of many developing and adult tissues. The mouse laminin alpha5 chain gene (Lama5) has been mapped close to the locus of the semidominant ragged (Ra) mutation on distal chromosome 2. The cause of the Ra mutation, which is usually lethal in the homozygous state, has not been determined. We have investigated whether a defect in Lama5 is responsible...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.