Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation.

doi:10.1016/s0014-5793(97)00686-8

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Article

Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation.

FEBS letters - 14 Jul 1997

Durkin M E, Loechel F, Mattei M G, Gilpin B J, Albrechtsen R, Wewer U M

Abstract excerpt

To investigate the function of the laminin alpha5-chain, previously identified in mice, cDNA clones encoding the 953-amino-acid carboxy terminal G-domain of the human laminin alpha5-chain were characterized. Northern blot analysis showed that the laminin alpha5-chain is expressed in human placent...

Topics

Amino Acid Sequence
Animals
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 20
Cloning, Molecular
Gene Expression Regulation
Genetic Linkage
Humans
In Situ Hybridization
Laminin
Mice
Molecular Sequence Data
Mutation
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 9271224
DOI: 10.1016/s0014-5793(97)00686-8

Genes

LAMA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9271224-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Sequence Analysis, DNA

Sequence Homology, Amino Acid