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Article

Characterization of the Epstein-Barr virus BZLF1 protein transactivation domain

1 Feb 1992

Abstract excerpt

Initiation of the Epstein-Barr virus (EBV) lytic cycle is dependent on expression of the viral transactivator Zta, which is encoded by the BZLF1 gene. Described here is an initial mapping of the regions of Zta involved in activating transcription. The data indicate that the amino-terminal 153 amino acids of Zta are important for activity, and in particular the region from residues 28 to 78 appears to be critical...

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Identifiers

PMID: 1309920
DOI: 10.1128/jvi.66.2.922-929.1992

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