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Article

Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors.

Journal of virology - 1 Oct 1998

Moutouh L, Estaquier J, Richman D D, Corbeil J

Abstract excerpt

We have previously shown that the presence of the CD4 cytoplasmic tail is critical for human immunodeficiency virus (HIV)-induced apoptosis (J. Corbeil, M. Tremblay, and D. D. Richman, J. Exp. Med. 183:39-48, 1996). We have pursued our investigation of the role of the CD4 transduction pathway in HIV-induced apoptosis. To do this, wild-type and mutant forms of the CD4 cytoplasmic tail were stably expressed in the...

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Identifiers

PMID: 9733846
DOI: 10.1128/JVI.72.10.8061-8072.1998
PMCID: PMC110143

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