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Article

Dictyostelium TRFA homologous to yeast Ssn6 is required for normal growth and early development.

The Journal of biological chemistry - 18 Sept 1998

Saito J, Kon T, Nagasaki A, Adachi H, Sutoh K

Abstract excerpt

The TPR (tetratricopeptide repeat) family became widespread during evolution, having been found from bacteria to mammals. By means of restriction enzyme-mediated integration, we have identified a Dictyostelium gene (trfA) highly homologous to a Saccharomyces cerevisiae gene encoding a TPR protein, Ssn6 (Cyc8), which functions as a global transcriptional repressor for diverse genes. The deduced amino acid sequence...

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Source

Identifiers

PMID: 9733762
DOI: 10.1074/jbc.273.38.24654

Genes

TPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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