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Article

Heterogeneous activation thresholds to cytokines in genetically distinct endothelial cells: evidence for diverse transcriptional responses.

Proceedings of the National Academy of Sciences of the United States of America - 26 Apr 1994

Bender J R, Sadeghi M M, Watson C, Pfau S, Pardi R

Abstract excerpt

It is well accepted that the induction of endothelial cell (EC) adhesion molecules is a critical component in acute inflammatory responses as well as allogeneic interactions in vascularized allografts and, possibly, atherogenesis. The "inflammatory triad" of interleukin 1 (IL-1), tumor necrosis factor, and lipopolysaccharide are potent stimulators of the EC activation/adhesion molecules intercellular adhesion...

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Identifiers

PMID: 7513430
DOI: 10.1073/pnas.91.9.3994
PMCID: PMC43709

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