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Article

Monocyte Siglec-14 expression is upregulated in patients with systemic lupus erythematosus and correlates with lupus disease activity.

Rheumatology (Oxford, England) - 1 Jun 2017

Thornhill Susannah I, Mak Anselm, Lee Bernett, Lee Hui Yin, Poidinger Michael, Connolly John E, Fairhurst Anna-Marie

Abstract excerpt

Objective: Siglecs are sialic acid-binding immunoglobulin-like lectins expressed on the surface of immune cells, which participate in the discrimination of self and non-self. We investigated myeloid CD33-related Siglec expression in a cohort of patients with SLE. Methods: Cell surface expression of Siglec-5/14, Siglec-9 and Siglec-10 on peripheral myeloid subsets were analysed from 39 SLE patients using flow...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28137763
DOI: 10.1093/rheumatology/kew498
PMCID: PMC5445601

Genes

SIGLEC14
SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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