Article
Interleukin-5 expression in the bone marrow of sensitized Balb/c mice after allergen challenge.
American journal of respiratory and critical care medicine - 1 Sept 1998
Minshall E M, Schleimer R, Cameron L, Minnicozzi M, Egan R W, Gutierrez-Ramos J C, Eidelman D H, Hamid Q
Abstract excerpt
Interleukin-5 (IL-5) is a potent eosinophilopoietic factor implicated in the chronic inflammatory cell accumulation accompanying bronchial asthma. However, its role in stimulating eosinophil differentiation within the bone marrow following allergen exposure remains to be elucidated. The aims of o...
Topics
- Allergens
- Animals
- Antigens, CD34
- Asthma
- Blood Proteins
- Bone Marrow
- CD3 Complex
- Cell Differentiation
- Eosinophil Granule Proteins
- Eosinophils
- Gene Expression Regulation
- Hematopoietic Stem Cells
- Immunization
- Immunohistochemistry
- In Situ Hybridization
- Inflammation Mediators
- Interleukin-5
- Male