Article
Changes in CD11b and L-selectin expression on eosinophils are mediated by human lung fibroblasts in vitro.
American journal of respiratory and critical care medicine - 1 Sept 1998
Spoelstra F M, Hovenga H, Noordhoek J A, Postma D S, Kauffman H F
Abstract excerpt
Eosinophilic airway infiltration is a central feature in asthma. Eosinophils recovered from bronchoalveolar fluid show an activated phenotype, e.g., increased CD11b and decreased L-selectin expression. We investigated whether lung fibroblasts are able to activate eosinophils in vitro, and if so, which activating factor is most important. CD11b and L-selectin expression of isolated peripheral blood eosinophils...
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