Article
Familial correlation of immunoglobulin G subclass responses to Plasmodium falciparum antigens in Burkina Faso.
Infection and immunity - 1 Feb 2001
Aucan C, Traoré Y, Fumoux F, Rihet P
Abstract excerpt
Host genes are thought to determine the immune response to malaria infection and the outcome. Cytophilic antibodies have been associated with protection, whereas noncytophilic antibodies against the same epitopes may block the protective activity of the protective ones. To assess the contribution of genetic factors to immunoglobulin G (IgG) subclass responses against conserved epitopes and Plasmodium falciparum...
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