Article
apterous, a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins.
Genes & development - 1 May 1992
Cohen B, McGuffin M E, Pfeifle C, Segal D, Cohen S M
Abstract excerpt
The apterous (ap) gene is required for the normal development of the wing and haltere imaginal discs in Drosophila melanogaster. ap encodes a new member of the LIM family of developmental regulatory genes. The deduced amino acid sequence of ap predicts a homeo domain and a cysteine/histidine-rich domain known as the LIM domain. In these domains ap is highly similar to the mec-3 and lin-11 proteins of...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Differentiation
- Cloning, Molecular
- DNA Transposable Elements
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Gene Expression Regulation
- Genes, Homeobox