Glucocorticoid-induced apoptosis and regulation of NF-kappaB activity in human leukemic T cells.

doi:10.1210/endo.139.9.6180

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Article

Glucocorticoid-induced apoptosis and regulation of NF-kappaB activity in human leukemic T cells.

Endocrinology - 1 Sept 1998

Ramdas J, Harmon J M

Abstract excerpt

Glucocorticoid-induced apoptosis was investigated in glucocorticoid-sensitive 6TG1.1 and resistant ICR27TK.3 human leukemic T cells. Following glucocorticoid treatment of 6TG1.1 cells, chromatin fragmentation was observed after a delay of 24 h. Fragmentation was not observed in ICR27TK.3 cells co...

Topics

Apoptosis
Chromatin
DNA Fragmentation
Dexamethasone
Drug Resistance
Glucocorticoids
Humans
Leukemia
Mifepristone
Mutation
NF-kappa B
Receptors, Glucocorticoid
T-Lymphocytes
Tetradecanoylphorbol Acetate
Tumor Cells, Cultured

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