Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages.

doi:10.1016/s0165-4608(98)00029-6

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Article

Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages.

Cancer genetics and cytogenetics - 1 Sept 1998

Butler M G, Tilburt J, DeVries A, Muralidhar B, Aue G, Hedges L, Atkinson J, Schwartz H

Abstract excerpt

Telomere DNA, at the ends of each chromosome, is conserved in nature and required for chromosome replication and stability. Reduction in telomere length has been observed in several malignancies as well as in leukocytes from healthy persons with advancing age. There is a paucity of data regarding...

Topics

Adolescent
Adult
Age Factors
Aged
Blotting, Southern
Child, Preschool
Female
Genetic Variation
Gestational Age
Humans
In Situ Hybridization
Male
Middle Aged
Skin
Telomere
Tissue Distribution

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