Article
Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages.
Cancer genetics and cytogenetics - 1 Sept 1998
Butler M G, Tilburt J, DeVries A, Muralidhar B, Aue G, Hedges L, Atkinson J, Schwartz H
Abstract excerpt
Telomere DNA, at the ends of each chromosome, is conserved in nature and required for chromosome replication and stability. Reduction in telomere length has been observed in several malignancies as well as in leukocytes from healthy persons with advancing age. There is a paucity of data regarding telomere length and the effects of in vivo aging in different tissues. These data could be helpful in interpreting...
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