Article
Measuring spontaneous deleterious mutation process.
Genetica - 1 Jan 1998
Kondrashov A S
Abstract excerpt
Parameters of the deleterious mutation process can be estimated using the data on genotypes, phenotypes, or fitnesses. These data can be on long-term evolution, on short-term changes, or on the properties of equilibrium populations. The two most important parameters at the genomic level, the total deleterious mutation rate U and the mutational pressure on fitness P, remain poorly known. Reliable data on the rates...
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