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Article

Does nonneutral evolution shape observed patterns of DNA variation in animal mitochondrial genomes?

Annual review of genetics - 1 Jan 2001

Gerber A S, Loggins R, Kumar S, Dowling T E

Abstract excerpt

Early studies of animal mitochondrial DNA (mtDNA) assumed that nucleotide sequence variation was neutral. Recent analyses of sequences from a variety of taxa have brought the validity of this assumption into question. Here we review analytical methods used to test for neutrality and evidence for nonneutral evolution of animal mtDNA. Evaluations of mitochondrial haplotypes in different nuclear backgrounds...

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PMID: 11700293
DOI: 10.1146/annurev.genet.35.102401.091106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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