Article
Contrasting patterns of nonneutral evolution in proteins encoded in nuclear and mitochondrial genomes.
Genetics - 1 Sept 2000
Weinreich D M, Rand D M
Abstract excerpt
We report that patterns of nonneutral DNA sequence evolution among published nuclear and mitochondrially encoded protein-coding loci differ significantly in animals. Whereas an apparent excess of amino acid polymorphism is seen in most (25/31) mitochondrial genes, this pattern is seen in fewer than half (15/36) of the nuclear data sets. This differentiation is even greater among data sets with significant...
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