Genomic heterogeneity of background substitutional patterns in Drosophila melanogaster.

doi:10.1534/genetics.104.032250

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Article

Genomic heterogeneity of background substitutional patterns in Drosophila melanogaster.

Genetics - 1 Feb 2005

Singh Nadia D, Arndt Peter F, Petrov Dmitri A

Abstract excerpt

Mutation is the underlying force that provides the variation upon which evolutionary forces can act. It is important to understand how mutation rates vary within genomes and how the probabilities of fixation of new mutations vary as well. If substitutional processes across the genome are heterogeneous, then examining patterns of coding sequence evolution without taking these underlying variations into account may...

Topics

Animals
Base Composition
Base Pairing
Chromosome Mapping
Codon
DNA Transposable Elements
Drosophila melanogaster
Euchromatin
Evolution, Molecular
Genetic Heterogeneity
Genetic Variation
Genome
Heterochromatin
Kinetics
Models, Genetic
Mutation
Recombination, Genetic

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Identifiers

PMID: 15520267
DOI: 10.1534/genetics.104.032250
PMCID: PMC1449091

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