Article
Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 1998
Lin H J, Probst-Hensch N M, Louie A D, Kau I H, Witte J S, Ingles S A, Frankl H D, Lee E R, Haile R W
Abstract excerpt
Cruciferous vegetables, especially broccoli, may prevent cancer through anticarcinogenic compounds. For example, broccoli contains isothiocyanates that induce carcinogen-detoxifying enzymes. Glutathione transferase enzymes conjugate isothiocyanates, leading to excretion. We hypothesized that broc...
Topics
- Adenoma
- Adult
- Aged
- Brassica
- California
- Case-Control Studies
- Colorectal Neoplasms
- Confidence Intervals
- Dietary Fiber
- Female
- Genotype
- Glutathione Transferase
- Humans
- Isothiocyanates
- Male