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Article

Genotype-Phenotype Correlation of Tracheal Cartilaginous Sleeves and Fgfr2 Mutations in Mice.

The Laryngoscope - 1 Apr 2021

Lam Austin S, Liu Carrie C, Deutsch Gail H, Rivera Joshua, Perkins Jonathan A, Holmes Greg, Jabs Ethylin W, Cunningham Michael L, Dahl John P

Abstract excerpt

OBJECTIVES: To characterize tracheal cartilage morphology in mouse models of fibroblast growth factor receptor (Fgfr2)-related craniosynostosis syndromes. To establish relationships between specific Fgfr2 mutations and tracheal cartilaginous sleeve (TCS) phenotypes in these mouse models. METHODS: Postnatal day 0 knock-in mouse lines with disease-specific genetic variations in the Fgfr2 gene (Fgfr2C342Y/C342Y ,...

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Identifiers

PMID: 32886384
DOI: 10.1002/lary.29060
PMCID: PMC7930142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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