Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Flt3L enhances the early stem cell compartment after ex vivo amplification of umbilical cord blood CD34+ cells.

Bone marrow transplantation - 1 Jul 1998

De Felice L, Di Pucchio T, Breccia M, Agostini F, Mascolo M G, Guglielmi C, Ricciardi M R, Screnci M, Tafuri A, Carmini D, Arcese W

Abstract excerpt

Umbilical cord blood (UCB) transplant represents a promising therapeutic approach, nevertheless this procedure has been so far almost exclusively used in pediatric patients because of the reduced volume of UCB units. The availability of larger numbers of early and late hematopoietic progenitors by ex vivo amplification procedure may allow the use of UCB in adults and improve the rate and time to engraftment. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD34
Share to Cell Compartmentation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to Fetal Blood

Share to Hematopoietic Stem Cells

Share to Leukocyte Common Antigens

Share to Membrane Proteins

Share to Phenotype

Source

Identifiers

PMID: 9715894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Flt3L enhances the early stem cell compartment after ex vivo amplification of umbilical cord blood CD34+ cells.PMID 9715894Read ↗

Interleukin 3 Improves the Ex Vivo Expansion of Primitive Human Cord Blood Progenitor Cells and Maintains the Engraftment Potential of SCID Repopulating CellsSemantic proximity Read ↗

Characterization of Serum-Free Ex Vivo–Expanded Hematopoietic Stem Cells Derived from Human Umbilical Cord Blood CD133 <sup>+</sup> CellsSemantic proximity Read ↗

Expansion of Human Cord Blood Hematopoietic Stem Cells for TransplantationSemantic proximity Read ↗

Cocultivation of umbilical cord blood cells with endothelial cells leads to extensive amplification of competent CD34+CD38- cells.Semantic proximity Read ↗

Long-term ex vivo expansion of human fetal liver primitive haematopoietic progenitor cells in stroma-free cultures.Semantic proximity Read ↗

Initial CD34+ cell-enrichment of cord blood determines hematopoietic stem/progenitor cell yield upon ex vivo expansion.Semantic proximity Read ↗

Insights into highly engraftable hematopoietic cells from 27-year cryopreserved umbilical cord bloodSemantic proximity Read ↗

Constitutive activation of Flt3 and STAT5A enhances self-renewal and alters differentiation of hematopoietic stem cells.Semantic proximity Read ↗

Phenotypic and functional characterization of committed and primitive myeloid and lymphoid hematopoietic precursors in human fetal liver.Semantic proximity Read ↗

Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cellsSemantic proximity Read ↗

CH02 Peptide Promotes CD34+ Umbilical Cord Blood Hematopoietic Stem Cells Ex Vivo ExpansionSemantic proximity Read ↗

Mesenchymal stem cells promote a primitive phenotype CD34+c-kit+ in human cord blood-derived hematopoietic stem cells during ex vivo expansionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.