Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cells

14 Aug 2020

Abstract excerpt

Abstract Background Although cord blood (CB) offers promise for treatment of patients with high-risk hematological malignancies and immune disorders, the limited numbers of hematopoietic stem cell (HSC)/progenitor cell in a CB unit and straitened circumstances in expanding ex vivo make it quite challenging to develop the successful cell therapies. Methods In this study, a novel strategy has been developed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Hematopoietic Stem Cell Transplantation
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32799928
DOI: 10.1186/s13287-020-01880-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cellsPMID 32799928Read ↗

Cord blood-derived early outgrowth endothelial progenitor cells.Semantic proximity Read ↗

Phenotypic and functional characterization of endothelial colony forming cells derived from human umbilical cord blood.Semantic proximity Read ↗

Endothelial and hematopoietic hPSCs differentiation via an hematoendothelial progenitor.Semantic proximity Read ↗

CH02 Peptide Promotes CD34+ Umbilical Cord Blood Hematopoietic Stem Cells Ex Vivo ExpansionSemantic proximity Read ↗

Generating human hematopoietic stem cells <i>in vitro</i> –exploring endothelial to hematopoietic transition as a portal for stemness acquisitionSemantic proximity Read ↗

Human umbilical cord is a unique and safe source of various types of stem cells suitable for treatment of hematological diseases and for regenerative medicineSemantic proximity Read ↗

Cocultivation of umbilical cord blood cells with endothelial cells leads to extensive amplification of competent CD34+CD38- cells.Semantic proximity Read ↗

Human Peripheral Blood-Derived Endothelial Colony-Forming Cells Are Highly Similar to Mature Vascular Endothelial Cells yet Demonstrate a Transitional Transcriptomic SignatureSemantic proximity Read ↗

Hypoxia drives hematopoiesis with the enhancement of T lineage through eliciting arterial specification of hematopoietic endothelial progenitors from hESCSemantic proximity Read ↗

Endothelial progenitor cells: past, state of the art, and future.Semantic proximity Read ↗

Insights into highly engraftable hematopoietic cells from 27-year cryopreserved umbilical cord bloodSemantic proximity Read ↗

Endothelial and Hematopoietic Cell Fate of Human Embryonic Stem Cells Originates from Primitive Endothelium with Hemangioblastic PropertiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.