Article
Oropharyngeal candidiasis in HIV(+) patients may influence the selection of HIV-1 protease variants.
Virus research - 1 Aug 2002
Hickman Peter J, Leigh Janet E, Mera Robertino M, Fidel Paul L, Luftig Ronald B
Abstract excerpt
Approximately 500 HIV-1 protease gene (pro) sequences were obtained from oral tissues (gingival cuff, buccal mucosa, tongue, palate) as well as saliva and peripheral blood mononuclear cells (PBMC) of 80 HIV-1 positive patients by nested amplification and manual sequencing of PCR products. By visual inspection each patient in this study exhibited a unique sequence profile. HIV-1 pro sequences obtained from...
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