Article
Resolution of complex feline leukocyte antigen DRB loci by reference strand-mediated conformational analysis (RSCA).
Tissue antigens - 1 Oct 2003
Kennedy L J, Ryvar R, Brown J J, Ollier W E R, Radford A D
Abstract excerpt
The DRB genes of the domestic cat are highly polymorphic. Studies based on clonal sequence analysis have suggested the existence of two distinct loci within individual animals and good evidence for 24 distinct FLA-DRB alleles. This variability, the complexity of clonal sequence analysis and its susceptibility to PCR-induced artefacts has represented a bottleneck to further progress. In this study we have applied...
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