Article
Reference strand mediated conformation analysis resolves HLA-DRB1 typing ambiguities when matching for unrelated bone marrow transplantation.
Tissue antigens - 1 Jul 2000
Corell A, Pay A L, Little A M, Hoddinott M A, Argüello J R, Borton M, Dunne C, Ogilvie H, O'Shea J, Madrigal J A, Marsh S G
Abstract excerpt
We show here the use of reference strand mediated conformation analysis (RSCA) to unambiguously resolve the HLA-DRB1 typing of two individuals which were selected as potential unrelated donors for bone marrow transplantation (BMT). In the first case, both sequence-specific primer (SSP) amplification and sequence-specific oligonucleotide probing (SSO), routinely used in different tissue typing laboratories gave,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.