Enhancement of chemosensitivity in human bladder cancer cells by adenoviral-mediated p53 gene transfer.

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Article

Enhancement of chemosensitivity in human bladder cancer cells by adenoviral-mediated p53 gene transfer.

Anticancer research - 1 Jan 2000

Miyake H, Hara I, Gohji K, Yamanaka K, Arakawa S, Kamidono S

Abstract excerpt

BACKGROUND: Drug resistance is a major problem in tumor chemotherapy, and recent studies have suggested that the differential sensitivity of cancer cells to chemotherapy is associated with different susceptibilities to undergoing apoptosis. The aim of this study was to evaluate the effects of int...

Topics

Adenoviridae
Animals
Antineoplastic Agents
Apoptosis
Cisplatin
Combined Modality Therapy
Cyclin-Dependent Kinase Inhibitor p21
Cyclins
Drug Screening Assays, Antitumor
Gene Transfer Techniques
Genes, p53
Humans
Male
Mice
Mice, Inbred BALB C
Mutation
Tumor Cells, Cultured
Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 9713515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9713515-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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